What Is Selank? A Complete Research Overview
This content is for laboratory research purposes only. Not for human or animal use.
Selank is a synthetic heptapeptide — a chain of seven amino acids (Thr-Lys-Pro-Arg-Pro-Gly-Pro) structurally related to the immune-regulating peptide tuftsin. Studied in the laboratory for its role in neurochemical signalling, immune modulation and anxiety-related behaviour models, it is supplied as a lyophilised powder. This guide explains what the peptide is, how it works, what it is used for in research, and the purity and storage points that matter when working with it.
Table of Contents
What Is Selank?
Selank is a synthetic peptide consisting of seven amino acids with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is structurally related to the naturally occurring tetrapeptide tuftsin, which is involved in immune system regulation. Selank is supplied as a lyophilised powder for controlled laboratory research investigations.
In scientific literature, Selank has been examined in experimental studies investigating peptide signalling behaviour, neurochemical pathways, and immune modulation within defined laboratory models.
How It Works
Selank is believed to influence the expression of certain neurotrophic factors and cytokines, which are proteins involved in cell signalling and immune responses. Research suggests Selank may affect the balance of key neurotransmitters, including serotonin and dopamine. Its ability to bind to specific receptors in the brain makes it a compound of interest for researchers investigating neurological and immunological pathways.
Selank Research Applications
Selank has been referenced in controlled in-vitro and experimental laboratory studies examining:
- Neurochemical signalling pathways: Research into how peptides influence neurotransmitter balance
- Immune system modulation: Studies on the peptide’s role in immune response regulation
- Anxiety-related behaviour models: Investigations into peptide-receptor interactions
- Neuroprotective mechanisms: Research into cellular protection pathways
- Peptide-receptor interaction dynamics: Studies on binding behaviour and downstream effects
Selank Purity and Quality
For reproducible results, confirm the identity and purity of the material before use. The specifications below are a useful checklist.
| Property | Specification |
|---|---|
| Appearance | White lyophilised powder |
| HPLC purity | ≥98% (HPLC-verified) |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Molecular weight | ~752.9 g/mol |
| Storage | -20°C, protected from light and moisture |
| COA | Confirms purity, molecular weight and peptide sequence |
Truncated sequences and impurities can confound an assay, so a batch Certificate of Analysis confirming the sequence and HPLC purity is essential. See why peptide purity matters for more on why this underpins reliable research data.
Reconstitution and Handling
The peptide is supplied as a lyophilised powder and is brought into solution before use. For aqueous preparations, bacteriostatic water is commonly used, as its preservative allows a single vial to serve multiple withdrawals under sterile technique. Bring the vial and solvent to room temperature, add the solvent gently down the inside wall, and swirl until fully dissolved. Aliquot the reconstituted solution and store frozen (-80°C for longer-term storage) to minimise freeze-thaw cycles.
Related Research Compounds
- Thymosin Alpha-1 — immune modulation research; see our Thymosin Alpha-1 guide.
- KPV — inflammation and immune response research.
- Semax — cognitive and neurochemical research.
- NAD+ — cellular energy and ageing research.
Frequently Asked Questions
What is Selank used for in research?
Selank is studied for its potential role in neurochemical signalling, immune modulation, and anxiety-related behaviour models.
How is Selank supplied?
Selank is supplied as a lyophilised powder in sterile vials, ready for reconstitution in research settings.
What purity should I look for?
For most research applications, ≥98% HPLC purity is recommended. Higher purity (≥99%) is preferred for sensitive assays.
How should Selank be stored?
Selank should be stored at -20°C, protected from light and moisture. Once reconstituted, aliquot and store at -80°C.
What is the molecular weight of Selank?
The molecular weight of Selank is approximately 752.9 g/mol.
For Research at Optimus Labs
Optimus Labs supplies Selank as a high-purity lyophilised powder, HPLC-verified and batch-tested, with a Certificate of Analysis confirming purity, molecular weight and peptide sequence. Orders ship from the UK with tracked delivery. Explore the rest of the research catalogue for related laboratory compounds, or our overview of the most popular research peptides in the UK.
References
- Zolotarev YA, et al. (2022). Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats. Bull Exp Biol Med. — pubmed.ncbi.nlm.nih.gov
- Seredin SB, et al. (2004). Selank – a new peptide with anxiolytic activity. Eksp Klin Farmakol. — pubmed.ncbi.nlm.nih.gov
- Kolik LG, et al. (2013). The effect of Selank on the development of tolerance to the analgesic effect of morphine in rats. Eksp Klin Farmakol. — pubmed.ncbi.nlm.nih.gov
